Is Imitrex safe with high blood pressure?
Luckily for you, Imitrex does not interact with most commonly prescribed medications for high blood pressure. With that said, it should not be prescribed to people with certain cardiovascular conditions such as coronary artery disease.
Sumatriptan can tighten your blood vessels and raise your blood pressure. It shouldn't be used with other triptans or a class of medications called ergot derivatives. The combination could lead to dangerously high blood pressure.
Options include: Blood pressure-lowering medications. These include beta blockers such as propranolol (Inderal, InnoPran XL, others) and metoprolol tartrate (Lopressor). Calcium channel blockers such as verapamil (Verelan) can be helpful in preventing migraines with aura.
For people with uncontrolled high blood pressure: Sumatriptan can increase your blood pressure. If you have high blood pressure that's not controlled, you should not take this medication. For people with serious liver disease: You should not use sumatriptan.
You should not use this medicine if you have used an MAO inhibitor (MAOI) such as phenelzine (Nardil®) or tranylcypromine (Parnate®) within the past 2 weeks. Do not use this medicine if you have taken other triptan migraine medicines or ergot-type medicines within the past 24 hours.
by Drugs.com
For those adults with moderate-to-severe migraine attacks that cannot tolerate triptans or who have found them ineffective, Ubrelvy is beneficial for treating migraines compared to no treatment. Ubrelvy is associated with fewer side effects than Imitrex, but is more expensive, costing almost twice as much.
Acetaminophen (Tylenol) is often the pain reliever of choice for people with high blood pressure (hypertension) because most other options are types of nonsteroidal anti-inflammatory drugs like ibuprofen (Motrin, Advil) or naproxen (Naprosyn, Aleve), which can raise blood pressure.
Results: Compared with placebo and expressed as weighted mean +/- SD, 100 mg sumatriptan increased aortic systolic blood pressure by 6 +/- 5 mm Hg (P < . 01), aortic pulse wave velocity by 0.5 +/- 0.5 m/s (P < . 01), and aortic augmentation index by 13% +/- 6% (P < . 0001).
This medicine may increase your risk of having abnormal heart rhythm, heart attack, angina, or stroke. This is more likely to occur if you or a family member already has heart disease, if you have diabetes, high blood pressure, high cholesterol, or if you smoke.
Headaches triggered by high blood pressure typically cause a pulsing sensation that's felt all over the head rather than on just one side. If your headache is severe, happens suddenly, or is accompanied by chest pain or shortness of breath, get immediate medical attention.
Does high blood pressure have anything to do with migraines?
Recurring migraine attacks can be a sign that you have high blood pressure, also called hypertension, but migraine disease can also put you at a higher risk of developing high blood pressure.
If you have an intractable migraine, or status migrainosus: Your ER doctor may give you a drug called dihydroergotamine (DHE-45) as an injection or through an IV, along with metoclopramide. They may also give you valproate in an IV. You may need to check into the hospital for a few days of these treatments.

Certain HA drugs, such as the triptans, cannot be used in the older patients with established cardiovascular disease, since the risk of vasospasm is too high [22].
Triptans are still the first choice therapy for acute migraine attacks. However, according to the terms of approval, triptans are contraindicated in uncontrolled arterial hypertension, coronary artery disease (CAD), and in patients after stroke or transient ischemic attack (TIA).
In rare cases, Imitrex can cause a heart attack. Your risk of heart attack may be higher if you have certain risk factors for heart disease. Risk factors include older age, high cholesterol, high blood pressure, obesity, diabetes, smoking, or a family history of heart disease.
do not take sumatriptan if you are taking a monoamine oxidase A (MAO-A) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) or if you have taken one of these medications in the past 2 weeks.
Imitrex is available as a generic drug called sumatriptan. A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be as safe and effective as the original drug.
The most commonly prescribed class of drugs for migraine are the triptans. These are all meant to be taken on an as-needed basis, at the first sign of headache, and they include Sumatriptan (Imitrex); Zolmitriptan (Zomig); Rizatriptan (Maxalt); and Eletriptan (Relpax).
Using Imitrex too often may cause a medication overuse headache (rebound headache). With this side effect, migraine may occur more often, you may develop more cluster headaches, or you may feel migraine-like pain every day.
- OTC treatments, such as acetaminophen or Excedrin.
- nonsteroidal anti-inflammatory drugs, such as aspirin or ibuprofen.
- prescription migraine medications, such as triptans, ergotamine, beta-blockers, or calcitonin gene-related peptide antagonists.
What is a natural replacement for sumatriptan?
A 250-mg dose of powdered ginger can be just as effective as sumatriptan in staving off the severity of acute migraines, according to a new study of 100 adult migraine patients.
The American Heart Association (AHA) has long recommended acetaminophen (Tylenol) as a safe alternative to nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve).
- Decongestants, such as those that contain pseudoephedrine.
- Pain medicines (NSAIDs), such as ibuprofen and naproxen.
- Cold and influenza (flu) medicines. ...
- Some antacids and other stomach medicines. ...
- Some natural health products.
- Maintaining a healthy weight.
- Exercising regularly.
- Managing stress.
- Eating a balanced diet that is low in salt.
- Limiting or avoiding alcohol.
- Not smoking.
- Getting enough sleep.
- Taking medications as directed.
Flushing, feelings of tingling/numbness/prickling/heat, tiredness, weakness, drowsiness, or dizziness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Background: Triptans are widely used to treat migraine but have been associated with stroke, myocardial infarction (MI), and ischemic heart disease (IHD) in case reports.
Imitrex starts working as soon as you take your dose. In most cases, you should notice relief of your symptoms within 2 hours. In some cases, the medication may work more quickly. For example, the injectable form of Imitrex may work to reduce symptoms within 5 to 20 minutes.
- ergotamine.
- dihydroergotamine.
- methysergide.
- any other triptan-containing medicine, eg zolmitriptan, almotriptan, eletriptan, frovatriptan, rizatriptan, naratriptan, sumatriptan.
Acetaminophen (Tylenol) is often the pain reliever of choice for people with high blood pressure (hypertension) because most other options are types of nonsteroidal anti-inflammatory drugs like ibuprofen (Motrin, Advil) or naproxen (Naprosyn, Aleve), which can raise blood pressure.
Stimulants: Sumatriptan causes blood vessels to narrow, raising blood pressure. In fact, sumatriptan taken all by itself can produce hypertensive crisis, a medical emergency in which blood pressure is raised too high.
Can you take triptans with high blood pressure?
Triptans are still the first choice therapy for acute migraine attacks. However, according to the terms of approval, triptans are contraindicated in uncontrolled arterial hypertension, coronary artery disease (CAD), and in patients after stroke or transient ischemic attack (TIA).
Most of the time, high blood pressure does not cause symptoms. The only case where hypertension appears to cause a headache is with a hypertensive crisis. This occurs when blood pressure soars to 180/120 mm Hg or higher and is associated with symptoms of end organ damage.
This medicine may increase your risk of having abnormal heart rhythm, heart attack, angina, or stroke. This is more likely to occur if you or a family member already has heart disease, if you have diabetes, high blood pressure, high cholesterol, or if you smoke.
- Cardiovascular problems, such as heart attack or unstable angina (type of chest pain). ...
- Cerebrovascular problems (disorders related to the brain and its blood vessels), such as stroke. ...
- Arrythmia (irregular heart rate or rhythm).
Some studies have found that migraines correlate somewhat with lower systolic but higher diastolic blood pressure. In fact, some studies have found a link between migraines and low blood pressure. Migraines also seem to be more frequent in people who have chronic high blood pressure that isn't well-managed.
Interactions between your drugs
No interactions were found between Imitrex Nasal and lisinopril.
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